DTI-TK News

DTI-TK officially listed as a FSL plugin

Gary Hui Zhang — Fri, 22 Feb 2013 6:12:16 GMT

Dear all,

Pleased to announce that DTI-TK is now officially listed as a FSL plugin. Through the two-way interoperability support provided by DTI-TK, FSL users can continue to take advantage of the powerful tract-based spatial statistics (TBSS) framework with the additional benefit of the state-of-the-art tensor-based DTI registration powered by DTI-TK.

For detail, please visit

http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/Plugins

Gary

Introducing a longitudinal DTI analysis pipeline with DTI-TK

Gary Hui Zhang — Tue, 05 Feb 2013 4:41:15 GMT

Dear all,

I'm extremely excited to report that DTI-TK now delivers a major new application area:

Unbiased longitudinal DTI analysis.

This new framework is the first to apply our state-of-the-art tensor-based registration to accurately quantify longitudinal changes of tissue microstructure as assessed by DTI.

The framework is reported in our Neuroimage paper (in press):

http://dx.doi.org/10.1016/j.neuroimage.2013.01.044

Our evaluation demonstrates its superior specificity and sensitivity, which can be particular important for detecting early changes in many neurological disorders, such as dementia.

Gary

Standardized vs Study-Specific DTI templates

Gary Hui Zhang — Sun, 07 Oct 2012 2:09:21 GMT

Recent research has generally advocated the use of study-specific templates, for spatial normalization, over standardized ones. The standardized template, although not always as accurate as one's own study-specific template, does offer substantial benefit in computational efficiency, as the latter will require an expensive iterative bootstrapping construction. So a useful question to ask here is whether there are circumstances the standardized template may offer a satisfactory alternative to study-specific ones. This is precisely what Shengwei Zhang and Konstantinos Arfanakis, from Illinois Institute of Technology, have investigated in their recent article "Role of standardized and study-specific human brain diffusion tensor templates in inter-subject spatial normalization" in Journal of Magnetic Resonance Imaging. If you are interested in knowing what they found, please click the link below:

http://onlinelibrary.wiley.com/doi/10.1002/jmri.23842/abstract

Gary

DTI-TK used to understand young children with autism

Gary Hui Zhang — Sat, 01 Sep 2012 12:47:43 GMT

A recent paper to appear in the prestigious journal of Biological Psychiatry examines young children with autism with diffusion tensor imaging. The paper is led by Lindsay Walker from Dr. Carlo Pierpaoli's group at NIH. The authors used DTI-TK for spatial normalization of diffusion tensor imaging data.

The paper can be found here: http://dx.doi.org/10.1016/j.biopsych.2012.08.001

Gary

DTI-TK used to detect WM changes before onset of psychosis

Gary Hui Zhang — Fri, 06 Apr 2012 9:16:59 GMT

A team from the Institute of Psychiatry, King's College London, used DTI-TK to help their investigation into pre-symptomatic brain changes in patients with psychosis. Their paper entitled "Alterations in White Matter Evident Before the Onset of Psychosis" is to appear in the prestigious journal of Schizophrenia Bulletin. For people who are interested, the link to the paper is attached below:

http://schizophreniabulletin.oxfordjournals.org/content/early/2012/04/03/schbul.sbs053.abstract

Gary

DTI-TK used to study vision loss in MS & optic neuritis

Gary Hui Zhang — Wed, 18 Jan 2012 10:58:23 GMT

A team from Monash University of Australia used DTI-TK to investigate visual impairment in multiple sclerosis and optic neuritis. Their paper entitled "Diffusion tensor imaging correlates of visual impairment in multiple sclerosis and chronic optic neuritis" is to appear in Investigative Ophthalmology & Visual Science, a top-ranked journal in the field of Ophthalmology. For interested readers, the full paper can be accessed with the following link:

http://www.iovs.org/content/early/2012/01/10/iovs.11-8864.abstract

Gary

DTI-TK used to understand brain integrity after stroke

Gary Hui Zhang — Sat, 14 Jan 2012 3:18:28 GMT

A team from NIH used DTI-TK to help their investigation into the functional and structural integrity in patients suffering chronic stroke. Their paper entitled "Parietofrontal integrity determines neural modulation associated with grasping imagery after stroke" is to appear in the highly prestigious journal of Brain. For people who are interested, the link to the paper is attached below:

http://brain.oxfordjournals.org/content/early/2012/01/08/brain.awr331.abstract

Gary

Recommended standard-space DTI template

Gary Hui Zhang — Fri, 04 Nov 2011 4:56:25 GMT

Hi all,

A belated note that a recent evaluation study from the group of Dr Arfanakis at the Illinois Institute of Technology showed that DTI-TK is particularly suited for the Enhanced ICBM template. I'm pleased to recommend this template for mapping your data to the MNI space either

- directly registering your data to this template with DTI-TK

or

- registering your local template to this template with DTI-TK

The latter option is described in the following tutorial:

http://dti-tk.sourceforge.net/pmwiki/pmwiki.php?n=Documentation.StdSpace

The tutorial provides the link to the evaluation study mentioned at above as well as the link to the Enhanced ICBM template.

Gary

DTI-TK helps constructing a DTI template for rhesus macaques

Gary Hui Zhang — Wed, 21 Sep 2011 3:39:04 GMT

Dr Nagesh Adluru from Prof Andrew Alexander's group at Wisconsin-Madison recently developed a first-of-its-kind DTI template for rhesus macaques. The DTI template is built from over 250 rhesus monkeys, the largest number ever used to build such a template. The template construction used an optimized version of DTI-TK tailored for monkey brains. The most recent release of DTI-TK has incorporated these optimizations and everyone can now benefit from this effort.

For further details of this template, please refer to Dr Adluru's NeuroImage paper here:

http://dx.doi.org/10.1016/j.neuroimage.2011.07.029

A video tutorial on group analysis in diffusion MRI

Gary Hui Zhang — Wed, 20 Jul 2011 2:29:34 GMT

This is a tutorial that I had the privilege of giving at the ISMRM 2011 weekend educational course on "Diffusion, Perfusion & the Corresponding Physiology". It aims to provide an overview on group analysis and atlases in the context of diffusion MRI. I hope you may find it useful.

http://www.nitrc.org/frs/downloadlink.php/3690

Gary Hui Zhang