Hi Dr. McClaren thank you for taking the time.

I re-downloaded the gPPI and made sure that it was active in the path, yet I received the same error.  I also tried with my ppi_wrapper script having P.WB = 0 and also received the same error.

Here is the full text:
Controls
Processing Group 1
Subject 1
Saving 04_analysis_rMRS_ROI_1.mat

ans =
04_analysis_rMRS_ROI_1.mat
Log File: 04_PPPI_5_19_2016_2.log
PPPI Version: 13.1.4-17-2014
Parameters used:
Processing subject: 04
VOI file : /Volumes/Promise_Pegasus/Active_Studies/K99/MRI_Data/Second_Levels/MASKS/rMRS_ROI_1.nii
Output file will be: 04_rMRS_ROI_1_session#_cond_PPI_regressors.txt
Contrast : No adjustment
Analysis : Psychophysiological Interactions
Extraction : mean
Tasks : _1_Fdbk_Wins_Fdbk_Losses_Win_Cue_Loss_Cue_Neu_Cue_Neu_Fdbk
Method : Condition Specific
VOI has 1331 voxels in 2x2x2 space
VOI has 1331 voxels in 2x2x2 space. This is in the the same space as the input data and functional mask.
VOI has 1331 voxels in 2x2x2 space
VOI has 1331 voxels in 2x2x2 space. This is in the the same space as the input data and functional mask.
SPM8: spm_fMRI_design (v4185) 14:57:34 - 19/05/2016
========================================================================
Saving fMRI design : ...SPM.mat saved
SPM8: spm_fmri_spm_ui (v4421) 14:57:35 - 19/05/2016
========================================================================
Mapping files : ...done
Calculating globals : ...done
Saving SPM configuration : ...SPM.mat saved
Design reporting : Estimation Failed
Warning: Missing conditions!!! Invalid Contrast
Invalid Contrast
PPI Contrasts were not estimated for some reason.