open-discussion > RE: Problem with SPHARM_Tutorial_Data_July2015
Jun 14, 2016  10:06 PM | Beatriz Paniagua
RE: Problem with SPHARM_Tutorial_Data_July2015
Hi Shahrokh,


Sorry for the delay in responding this question.

Is there a relationship between signed distance map and p-value map (e.g., mancovaRawP)?
Not necessarily. The p-value maps illustrate significantly different local shape changes between the two populations introduced in mancova. This is not related to the magnitude of the measurement.

I expected that there would be a direct relationship between signed distance and p-value color-coded maps. In other words, is it expected that p-values in the specific region, relation with other regions, reduces as signed magnitudes of the distance in this specific region (between mean surface of normal group and mean surface of OA group) is larger than other regions?
Again, not necessarily. See response above.
Can you analyze these images? Also, can you make relevant these images together in terms of color?
Thanks for sharing your images. Large magnitudes of change between the two means do not have to result in more significant changes. A lot of things are in play for example variability of the measurement in the region.
The outputs of shapeAnalysisMANCOVA_Wizard are meta files with the extensions as *_meanA.meta and *_meanB.meta. How can created these
surfaces? Is this mean surface can be representative of its group?
These means are the results of averaging the coordinate points of each one of the populations. The mean is just a way to describe your group, but of course it mean a data reduction. If your group includes a lot of shape variability it will be all averaged in the end, and it wont be able to represent the group well. Just curious, what is the n of each one of your groups?
The contents of files as *_mancovaBonferroniP.txt or *_mancovaFDRP.txt is 1 exactly!
That means that your p-values do not survive correction for false positives in the threshold you specified in the shapenalysismancova_wizard program.




I hope that helps.
Please, let me know if you have any further questions.



Best,

Beatriz

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shahrokh nasseri Apr 4, 2016
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RE: Problem with SPHARM_Tutorial_Data_July2015
Beatriz Paniagua Jun 14, 2016
shahrokh nasseri Jun 16, 2016