<br>
<div class="gmail_quote"><p class="MsoNormal" style="text-align: justify;"><b><span style="font-size: 10pt;">ANNOUNCING
A NEW CSH WORKSHOP ON CIRCUIT & MOLECULAR ARCHITECTURE OF THE VERTEBRATE
BRAIN</span></b></p>
<p class="MsoNormal" style="text-align: justify;"><span style="font-size: 10pt;"><br></span></p>
<p class="MsoNormal" style="text-align: justify;"><a name="12827697e5e1fe87_OLE_LINK2"></a><a name="12827697e5e1fe87_OLE_LINK1"><span><span style="font-size: 10pt;">Dear Colleague:</span></span></a></p><p class="MsoNormal" style="text-align: justify;">
<span><span><span style="font-size: 10pt;"></span></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span></span></span><a href="http://meetings.cshl.edu/courses/c-circuits10.shtml" target="_blank"><span><span><b><span style="font-size: 10pt;">WORKSHOP ON CIRCUIT & MOLECULAR ARCHITECTURE OF THE
VERTEBRATE BRAIN</span></b></span></span><span><span></span></span></a><span><span><b><span style="font-size: 10pt; color: navy; font-weight: normal;"></span></b></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><b><span style="font-size: 10pt; color: navy;">JUNE 17 –
29, 2010</span></b></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><b><span style="font-size: 10pt; color: navy;">Application
deadline:<span> </span>April 30, 2010</span></b></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;">Instructors:
Partha Mitra, Kathy Rockland
& Z. Josh Huang</span></span></span></p>
<p style="text-align: justify;"><span><span><i><span style="font-size: 10pt;">Please pass this
along to colleagues or members of your laboratory or group who may benefit from
this training. </span></i></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;">In
comparison with complete reference genomes now available for multiple species,
our knowledge about the neuronal and circuit architecture of the vertebrate
nervous systems is relatively sparse. However, this situation is rapidly
changing, enabled by technical advances as well as resurgent and widespread
interest in the neuroscientific community in mapping out neural circuitry at
unprecedented scales, ranging from the reconstruction of local micro-circuits
to the mapping of brain-wide meso-circuits. This circuit architecture naturally
and logically complements the molecular architecture as delineated by the
mapping of brain-wide gene expression patterns. Experimental efforts are under
way in multiple species, promising to advance our knowledge of the wiring logic
of the vertebrate brain. This will fundamentally impact our understanding of
brain function and evolution, and also play an essential role in understanding
pathological changes in circuitry that underlie neurological and
neuropsychiatric disorders.</span></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;"> </span></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;">This
two week workshop will bring together classical neuroanatomical approaches
along with the new techniques that are enabling a new generation of
neuroanatomical research into the circuit and molecular architecture of the
vertebrate brain. The workshop will have three main components: classical,
molecular and computational neuroanatomy. An experimental component of the
workshop will involve injection based tract tracing in the mouse, employing
classical and viral tracer substances, in wild type and transgenic mice.
Lectures will cover classical (tracer injections, sectioning, histochemistry,
imaging) and molecular (genetic engineering of mice as well as viral tracers,
optogenetic probing of circuits) techniques. Material will be presented by
simultaneous viewing of slides under light microscopy as well as digital
images, including an in-depth orientation to internet resources. The
computational component will involve hands on algorithmic analysis and
interpretation of digital neuroanatomical data sets, from both EM and light
microscopy. Species covered will include rodents, human and nonhuman primates,
with special lectures on other vertebrate lineages.</span></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;"> </span></span></span></p>
<p class="MsoNormal"><span><span><span style="font-size: 10pt;">Speakers include: John
Allman, David Amaral, Katrin Amunts, Jason Bohland, Mitya Cklovskii, Karl Deisseroth,
Bruce Fischl , Mike Hawrylycz , Mark Henkelman, Harvey Karten , David
Kleinfeld, Kevan Martin, Marcello Rosa, Joe Safdieh , Cliff Saper , Nenad
Sestan, Karel Svoboda , Larry Swanson, Menno Witter & Hongkui Zeng</span></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;"> </span></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;">Partial
scholarships may be available to offset tuition, room and board costs based on
stated need (apply in writing).</span></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;"> </span></span></span></p>
<p class="MsoNormal" style="text-align: justify;"><span><span><span style="font-size: 10pt;"> ***************************************</span></span></span></p>
<p class="MsoNormal"><span><span><span style="font-size: 10pt;">Cold</span><span style="font-size: 10pt;"> Spring Harbor</span><span style="font-size: 10pt;"> Laboratory</span></span></span></p>
<p class="MsoNormal"><span><span><span style="font-size: 10pt;">Meetings
& Courses Program</span></span></span></p>
<p class="MsoNormal"><span><span><span style="font-size: 10pt;"> </span></span></span></p>
<p class="MsoNormal"><span><span><span style="font-size: 10pt;">Please
</span></span></span><a href="http://meetings.cshl.edu/courses.html" target="_blank"><span><span><span style="font-size: 10pt;">click here</span></span></span><span><span></span></span></a><span><span><span style="font-size: 10pt;"> for our entire
course program for an up-to-the-minute and in-depth grasp of the latest
techniques and concepts across a wide range of biological disciplines:
For a full schedule of 2010 meetings, please </span></span></span><a href="http://meetings.cshl.edu/meetings.html" target="_blank"><span><span><span style="font-size: 10pt;">click
here</span></span></span><span><span></span></span></a><span><span><span style="font-size: 10pt;"></span></span></span></p>
<p class="MsoNormal"><span><span><span style="font-size: 10pt;"> </span></span></span></p>
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</div><br>