From NITRC Wiki

T1-Relaxometry with Double Echo Experiments

Prerequisites

• JIST Pre-Beta 1.3 or Newer: http://www.nitrc.org/frs/?group_id=228

References

• Bottomley P, Ouwerkerk R. The dual-angle method for fast, sensitive T1 measurement in vivo with low-angle adiabatic pulses. JMR B 1994;104:159-167
• Smith SA, Edden RAE, Barker PB, van Zijl PCM. Measurement of T1 and T2 in the Cervical Spinal Cord at 3Tesla. MRM 60:213-219 (2008) : http://www3.interscience.wiley.com/journal/120173564/abstract

Example

Method

• Download the layout file for double angle analysis : http://www.nitrc.org/frs/download.php/1097/T1-DoubleAngle-JIST.layout
• Sample data is not available at this time due to data-use restrictions.
• Load the layout file:

• Select "T1-Low" and specify a text file containing low-flip angle images for each subject.
• Select "T1-High" and specify a text file containing high-flip angle images for each subject.
• Select "MPRAGE" and specify a text file containing structural targets used for image registration.
• Select the "T1:DoubleAngle" module
  • Specify the "Low Flip Angle" in degrees
  • Specify the "High Flip Angle" in degrees
  • Specify the "Repetition Time" in milliseconds
• Select the copy files module and specify an output directory.
• Select Project->Layout preferences and specify an output directory.
• Select Project->Global preferences.
  • Ensure that you have selected the MIPAV JRE's for the java binary.
  • Otherwise, you must ensure that the MIPAV numerical libraries are on your default java classpath.
• Save the layout.
• Run the layout in the process manager.
• Enjoy your estimated T1 maps. The parameters are estimated in milliseconds.