Yes NITRC LDDMM Linux, Windows Yes C++ LDDMM assigns a metric distances on the space of anatomical images LDDMM Console (Text Based), Win32 (MS Windows), English, Production/Stable, C++, Shape Analysis, End Users, Linux, Windows, ANALYZE http://www.nitrc.org/projects/lddmm-volume/, http://cis.jhu.edu/software