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  <title>NITRC News Group Forum: semi-blind-independent-component-analysis-of-fmri-based-on-real-time-fmri-system.</title>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Semi-Blind Independent Component Analysis of fMRI Based on Real-Time fMRI System.&lt;/b&gt;&lt;/p&gt;
        &lt;p&gt;IEEE Trans Neural Syst Rehabil Eng. 2012 Jan 23;&lt;/p&gt;
        &lt;p&gt;Authors:  Ma X, Zhang H, Zhao X, Yao L, Long Z&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        Real-time functional magnetic resonance imaging (fMRI) is a type of neurofeedback tool that enables researchers to train individuals to actively gain control over their brain activation. Independent component analysis (ICA) based on data-driven model is seldom used in real-time fMRI studies due to large time cost, though it has been very popular to offline analysis of fMRI data. The feasibility of performing real-time ICA (rtICA) processing has been demonstrated by previous study. However, rtICA was only applied to analyze single-slice data rather than full-brain data. In order to improve the performance of rtICA, we proposed semi-blind real-time ICA (sb-rtICA) for our real-time fMRI system by adding regularization of certain estimated time courses using the experiment paradigm information to rtICA. Both simulated and real-time fMRI experiment were conducted to compare the two approaches. Results from simulated and real full-brain fMRI data demonstrate that sb-rtICA outperforms rtICA in robustness, computational time and spatial detection power. Moreover, in contrast to rtICA, the first component estimated by sb-rtICA tends to be the target component in more sliding windows.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 22275721 [PubMed - as supplied by publisher]&lt;/p&gt;
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