http://www.nitrc.org/forum/forum.php?forum_id=2541 <table border="0" width="100%"><tr><td align="left"/></tr></table> <p><b>Alteration of functional connectivity in tinnitus brain revealed by resting-state fMRI?: A pilot study.</b></p> <p>Int J Audiol. 2012 Jan 30;</p> <p>Authors: Kim JY, Kim YH, Lee S, Seo JH, Song HJ, Cho JH, Chang Y</p> <p>Abstract<br/> Objective: We report a case study on possible alterations in resting-state functional connectivity between the auditory network and non-auditory brain regions in tinnitus patients. Design: Independent component analyses were performed to evaluate coherent spontaneous activity in distributed brain networks. The resting-state functional connectivity scores between the right and left auditory networks were measured. Direct comparison of resting-state connectivity between tinnitus patients and controls was made using a two-sample t-test. Study sample: Four patients (three male, one female; mean age 45 ± 3.92 years) with chronic tinnitus lateralized to the left ear, and six age-matched controls (four male, two female; mean age 45 ± 2.76 years) participated in this case study. Results: The average resting-state functional connectivity (FC) score between the left and right auditory cortical regions was significantly lower in tinnitus patients than in controls (P &lt; 0.05). Direct comparison between patients and controls showed that increased functional connectivity caused by tinnitus occurred predominantly in the left amygdala and in the dorsomedial prefrontal cortex. Conclusions: Our pilot study suggested that resting state functional magnetic resonance imaging (fMRI) could be useful to investigate possible alterations in resting-state neuronal activity between the auditory and non-auditory networks in tinnitus patients.<br/> </p><p>PMID: 22283490 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Sun, 26 Apr 2026 13:01:28 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator