NITRC News Group Forum: morphological-homogeneity-of-neurons--searching-for-outlier-neuronal-cells

NITRC News Group Forum: morphological-homogeneity-of-neurons--searching-for-outlier-neuronal-cells http://www.nitrc.org/forum/forum.php?forum_id=3170 <div class="Abstract" lang="en"><a name="Abs1"></a>Abstract  <div class="normal">We report a morphology-based approach for the automatic identification of outlier neurons, as well as its application to the NeuroMorpho.org database, with more than 5,000 neurons. Each neuron in a given analysis is represented by a feature vector composed of 20 measurements, which are then projected into a two-dimensional space by applying principal component analysis. Bivariate kernel density estimation is then used to obtain the probability distribution for the group of cells, so that the cells with highest probabilities are understood as archetypes while those with the smallest probabilities are classified as outliers. The potential of the methodology is illustrated in several cases involving uniform cell types as well as cell types for specific animal species. The results provide insights regarding the distribution of cells, yielding single and multi-variate clusters, and they suggest that outlier cells tend to be more planar and tortuous. The proposed methodology can be used in several situations involving one or more categories of cells, as well as for detection of new categories and possible artifacts. </div> </div><ul> <li>Content Type Journal Article</li><li>Category Original Article</li><li>Pages 1-11</li><li>DOI 10.1007/s12021-012-9150-5</li><li>Authors<ul> <li>Krissia Zawadzki, Institute of Physics at São Carlos, University of São Paulo, PO Box 369, São Carlos, SP CEP 13.560-970, Brazil</li><li>Christoph Feenders, School of Computing Science, Newcastle University, Claremont Tower, Newcastle-upon-Tyne, NE1 7RU UK</li><li>Matheus P. Viana, Institute of Physics at São Carlos, University of São Paulo, PO Box 369, São Carlos, SP CEP 13.560-970, Brazil</li><li>Marcus Kaiser, School of Computing Science, Newcastle University, Claremont Tower, Newcastle-upon-Tyne, NE1 7RU UK</li><li>Luciano da F. Costa, Institute of Physics at São Carlos, University of São Paulo, PO Box 369, São Carlos, SP CEP 13.560-970, Brazil</li> </ul></li> </ul><ul class="parents"> <ul class="details"> <li>Journal <a href="http://www.springerlink.com/content/120559/">Neuroinformatics</a></li><li>Online ISSN 1559-0089</li><li>Print ISSN 1539-2791</li> </ul> </ul> en-us Copyright 2000-2026 NITRC OSI Mon, 20 Apr 2026 1:41:03 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator