http://www.nitrc.org/forum/forum.php?forum_id=3206 <p class="abstract"><div class="Abstract" lang="en"><a name="Abs1"></a><span class="AbstractHeading">Abstract&nbsp;&nbsp;</span><div class="normal">Current understanding of the synaptic organization of the brain depends to a large extent on knowledge about the synaptic inputs to the neurons. Indeed, the dendritic surfaces of pyramidal cells (the most common neuron in the cerebral cortex) are covered by thin protrusions named dendritic spines. These represent the targets of most excitatory synapses in the cerebral cortex and therefore, dendritic spines prove critical in learning, memory and cognition. This paper presents a new method that facilitates the analysis of the 3D structure of spine insertions in dendrites, providing insight on spine distribution patterns. This method is based both on the implementation of straightening and unrolling transformations to move the analysis process to a planar, unfolded arrangement, and on the design of DISPINE, an interactive environment that supports the visual analysis of 3D patterns. </div> </div></p><ul> <li><span class="labelName">Content Type </span><span class="labelValue">Journal Article</span></li><li>Category Original Article</li><li>Pages 1-17</li><li>DOI 10.1007/s12021-012-9153-2</li><li><span class="labelName">Authors</span><ul> <li>Juan Morales, Cajal Blue Brain Project, Universidad Politécnica de Madrid (UPM), Madrid, Spain</li><li>Ruth Benavides-Piccione, Laboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid (UPM), Madrid, Spain</li><li>Angel Rodríguez, Dept. de Arquitectura y Tecnología de Sistemas Informáticos, Universidad Politécnica de Madrid (UPM), Madrid, Spain</li><li>Luis Pastor, Dept. de Arquitectura y Tecnología de Computadores y Ciencia de la Computación e Inteligencia Artificial, Universidad Rey Juan Carlos (URJC), Madrid, Spain</li><li>Rafael Yuste, Howard Hughes Medical Institute, Columbia University, New York, NY 10027, USA</li><li>Javier DeFelipe, Laboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid (UPM), Madrid, Spain</li> </ul></li> </ul><ul class="parents"> <ul class="details"> <li><span class="header labelName">Journal </span><span class="labelValue"><a href="http://www.springerlink.com/content/120559/">Neuroinformatics</a></span></li><li><span class="labelName">Online ISSN </span><span class="labelValue">1559-0089</span></li><li><span class="labelName">Print ISSN </span><span class="labelValue">1539-2791</span></li> </ul> </ul> en-us Copyright 2000-2026 NITRC OSI Mon, 20 Apr 2026 3:07:17 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator