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  <title>NITRC News Group Forum: single-session-motor-learning-demonstrated-using-a-visuomotor-task--evidence-from-fmri-and-behavioural-analysis.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=3292</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed&amp;amp;cmd=Link&amp;amp;LinkName=PubMed_PubMed&amp;amp;from_uid=22743802&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Single session motor learning demonstrated using a visuomotor task: Evidence from fmri and behavioural analysis.&lt;/b&gt;&lt;/p&gt;
        &lt;p&gt;J Neurosci Methods. 2012 Jun 25;&lt;/p&gt;
        &lt;p&gt;Authors:  Boe SG, Cassidy RJ, McIlroy WE, Graham SJ&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        There is a continuing need to improve understanding of the central nervous system control of learning. Specifically, there is a need to examine the characteristics of cortical and sub-cortical activity linked to the stages of motor learning, including those occurring within a single-session. In this study we sought to design and investigate a visuomotor task to determine its ability to assess the component of motor learning occurring during a single session of fMRI (i.e., the 'online' improvement in motor performance). Fourteen healthy control subjects performed a visuomotor task requiring a combination of bilateral grip force to accurately move a cursor towards a target. We assessed online motor learning by comparing behavioural measures (accuracy and error magnitude) and the extent of spatial activation in specific brain regions of interest (ROIs) using fMRI pre- and post-training. Results showed a training-related improvement in performance based on increased accuracy (p&amp;lt;0.0125) and decreased error magnitude (p&amp;lt;0.0125) from pre- to post-training. Decreases in the extent of spatial activation from pre- to post-training in the majority of ROIs supported a training-related attenuation in brain activity associated with online motor learning. Importantly, decreases in error magnitude across conditions (p&amp;lt;0.05) confirmed that improvements in performance continued over the entire course of the experiment. Establishing this task may permit more extensive study of the neural correlates of single-session, online learning in healthy individuals and those with motor control challenges. Information obtained from such studies may provide an opportunity to improve interventions in neurological rehabilitation.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 22743802 [PubMed - as supplied by publisher]&lt;/p&gt;
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