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  <title>NITRC News Group Forum: high-resolution-functional-mri-at-3-t--3d-2d-echo-planar-imaging-with-optimized-physiological-noise-correction.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=3372</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed&amp;amp;cmd=Link&amp;amp;LinkName=PubMed_PubMed&amp;amp;from_uid=22821858&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;High-resolution functional MRI at 3 T: 3D/2D echo-planar imaging with optimized physiological noise correction.&lt;/b&gt;&lt;/p&gt;
        &lt;p&gt;Magn Reson Med. 2012 Jul 20;&lt;/p&gt;
        &lt;p&gt;Authors:  Lutti A, Thomas DL, Hutton C, Weiskopf N&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        High-resolution functional MRI (fMRI) offers unique possibilities for studying human functional neuroanatomy. Although high-resolution fMRI has proven its potential at 7 T, most fMRI studies are still performed at rather low spatial resolution at 3 T. We optimized and compared single-shot two-dimensional echo-planar imaging (EPI) and multishot three-dimensional EPI high-resolution fMRI protocols. We extended image-based physiological noise correction from two-dimensional EPI to multishot three-dimensional EPI. The functional sensitivity of both acquisition schemes was assessed in a visual fMRI experiment. The physiological noise correction increased the sensitivity significantly, can be easily applied, and requires simple recordings of pulse and respiration only. The combination of three-dimensional EPI with physiological noise correction provides exceptional sensitivity for 1.5 mm high-resolution fMRI at 3 T, increasing the temporal signal-to-noise ratio by more than 25% compared to two-dimensional EPI. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 22821858 [PubMed - as supplied by publisher]&lt;/p&gt;
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