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  <title>NITRC News Group Forum: a-statistical-framework-for-inter-group-image-registration</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=3445</link>
  <description>&lt;p class=&quot;abstract&quot;&gt;&lt;div class=&quot;Abstract&quot; lang=&quot;en&quot;&gt;&lt;a name=&quot;Abs1&quot;&gt;&lt;/a&gt;&lt;span class=&quot;AbstractHeading&quot;&gt;Abstract&amp;nbsp;&amp;nbsp;&lt;/span&gt;&lt;div class=&quot;normal&quot;&gt;Groupwise image registration plays an important role in medical image analysis. The principle of groupwise image registration
 is to align a given set of images to a hidden template space in an iteratively manner without explicitly selecting any individual
 image as the template. Although many approaches have been proposed to address the groupwise image registration problem for
 registering a single group of images, few attentions and efforts have been paid to the registration problem between two or
 more different groups of images. In this paper, we propose a statistical framework to address the registration problems between
 two different image groups. The main contributions of this paper lie in the following aspects: (1) In this paper, we demonstrate
 that directly registering the group mean images estimated from two different image groups is not sufficient to establish the
 reliable transformation from one image group to the other image group. (2) A novel statistical framework is proposed to extract
 anatomical features from the white matter, gray matter and cerebrospinal fluid tissue maps of all aligned images as morphological
 signatures for each voxel. The extracted features provide much richer anatomical information than the voxel intensity of the
 group mean image, and can be integrated with the multi-channel Demons registration algorithm to perform the registration process.
 (3) The proposed method has been extensively evaluated on two publicly available brain MRI databases: the LONI LPBA40 and
 the IXI databases, and it is also compared with a conventional inter-group image registration approach which directly performs
 deformable registration between the group mean images of two image groups. Experimental results show that the proposed method
 consistently achieves higher registration accuracy than the method under comparison.
 &lt;/div&gt;
 &lt;/div&gt;&lt;/p&gt;&lt;ul&gt;
	&lt;li&gt;&lt;span class=&quot;labelName&quot;&gt;Content Type &lt;/span&gt;&lt;span class=&quot;labelValue&quot;&gt;Journal Article&lt;/span&gt;&lt;/li&gt;&lt;li&gt;Category Original Article&lt;/li&gt;&lt;li&gt;Pages 1-12&lt;/li&gt;&lt;li&gt;DOI 10.1007/s12021-012-9156-z&lt;/li&gt;&lt;li&gt;&lt;span class=&quot;labelName&quot;&gt;Authors&lt;/span&gt;&lt;ul&gt;
		&lt;li&gt;Shu Liao, Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA&lt;/li&gt;&lt;li&gt;Guorong Wu, Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA&lt;/li&gt;&lt;li&gt;Dinggang Shen, Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA&lt;/li&gt;
	&lt;/ul&gt;&lt;/li&gt;
&lt;/ul&gt;&lt;ul class=&quot;parents&quot;&gt;
	&lt;ul class=&quot;details&quot;&gt;
		&lt;li&gt;&lt;span class=&quot;header labelName&quot;&gt;Journal &lt;/span&gt;&lt;span class=&quot;labelValue&quot;&gt;&lt;a href=&quot;http://www.springerlink.com/content/120559/&quot;&gt;Neuroinformatics&lt;/a&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span class=&quot;labelName&quot;&gt;Online ISSN &lt;/span&gt;&lt;span class=&quot;labelValue&quot;&gt;1559-0089&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span class=&quot;labelName&quot;&gt;Print ISSN &lt;/span&gt;&lt;span class=&quot;labelValue&quot;&gt;1539-2791&lt;/span&gt;&lt;/li&gt;
	&lt;/ul&gt;
&lt;/ul&gt;</description>
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