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  <title>NITRC News Group Forum: motor-and-non-motor-inhibition-in-the-go-nogo-task--an-erp-and-fmri-study.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=3451</link>
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        &lt;p&gt;&lt;b&gt;Motor and non-motor inhibition in the Go/NoGo task: An ERP and fMRI study.&lt;/b&gt;&lt;/p&gt;
        &lt;p&gt;Int J Psychophysiol. 2012 Aug 7;&lt;/p&gt;
        &lt;p&gt;Authors:  Smith JL, Jamadar S, Provost AL, Michie PT&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        The contribution of movement-related activity to Go/NoGo ERP differences has been debated for 25years. In this study, we examined ERP and fMRI measures of activity in twenty adults performing non-motor (count) and motor (right-handed button press) trials of the Go/NoGo task. Task performance was highly accurate and similar in the ERP and fMRI environments. No significant task-related effects were observed for the N2 component; however, we observed a substantial increase in positivity for Press NoGo compared to Count NoGo trials. The fMRI results also revealed significant deactivations for Press NoGo relative to Count NoGo trials in several left-lateralised motor-related areas, including the inferior frontal gyrus, precentral gyrus and supplementary motor area. Together, the results indicate that the P3 NoGo&amp;gt;Go effect in motor tasks is caused not by movement-related negativity on Go trials but by inhibition-related positivity on NoGo trials, and that this is associated with deactivation of motor areas involved in the Go response.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 22885679 [PubMed - as supplied by publisher]&lt;/p&gt;
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