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  <title>NITRC News Group Forum: automated-segmentation-of-mouse-brain-images-using-multi-atlas-multi-roi-deformation-and-label-fusion</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=3600</link>
  <description>&lt;p class=&quot;abstract&quot;&gt;&lt;div class=&quot;Abstract&quot; lang=&quot;en&quot;&gt;&lt;a name=&quot;Abs1&quot;&gt;&lt;/a&gt;&lt;span class=&quot;AbstractHeading&quot;&gt;Abstract&amp;nbsp;&amp;nbsp;&lt;/span&gt;&lt;div class=&quot;normal&quot;&gt;We propose an automated multi-atlas and multi-ROI based segmentation method for both skull-stripping of mouse brain and the
 ROI-labeling of mouse brain structures from the three dimensional (3D) magnetic resonance images (MRI). Three main steps are
 involved in our method. First, a region of interest (ROI) guided warping algorithm is designed to register multi-atlas images
 to the subject space, by considering more on the matching of image contents around the ROI boundaries which are more important
 for ROI labeling. Then, a multi-atlas and multi-ROI based deformable segmentation method is adopted to refine the ROI labeling
 result by deforming each ROI surface via boundary recognizers (i.e., SVM classifiers) trained on local surface patches. Finally,
 a local-mutual-information (MI) based multi-label fusion technique is proposed for allowing the atlases with better local
 image similarity with the subject to have more contributions in label fusion. The experimental results show that our method
 works better than the conventional methods on both in vitro and in vivo mouse brain datasets.
 &lt;/div&gt;
 &lt;/div&gt;&lt;/p&gt;&lt;ul&gt;
	&lt;li&gt;&lt;span class=&quot;labelName&quot;&gt;Content Type &lt;/span&gt;&lt;span class=&quot;labelValue&quot;&gt;Journal Article&lt;/span&gt;&lt;/li&gt;&lt;li&gt;Category Original Article&lt;/li&gt;&lt;li&gt;Pages 1-11&lt;/li&gt;&lt;li&gt;DOI 10.1007/s12021-012-9163-0&lt;/li&gt;&lt;li&gt;&lt;span class=&quot;labelName&quot;&gt;Authors&lt;/span&gt;&lt;ul&gt;
		&lt;li&gt;Jingxin Nie, Department of Radiology and BRIC, University of North Carolina at Chapel Hill, School of Medicine, MRI Building, CB #7513, 106 Mason Farm Road, Chapel Hill, NC 27599, USA&lt;/li&gt;&lt;li&gt;Dinggang Shen, Department of Radiology and BRIC, University of North Carolina at Chapel Hill, School of Medicine, MRI Building, CB #7513, 106 Mason Farm Road, Chapel Hill, NC 27599, USA&lt;/li&gt;
	&lt;/ul&gt;&lt;/li&gt;
&lt;/ul&gt;&lt;ul class=&quot;parents&quot;&gt;
	&lt;ul class=&quot;details&quot;&gt;
		&lt;li&gt;&lt;span class=&quot;header labelName&quot;&gt;Journal &lt;/span&gt;&lt;span class=&quot;labelValue&quot;&gt;&lt;a href=&quot;http://www.springerlink.com/content/120559/&quot;&gt;Neuroinformatics&lt;/a&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span class=&quot;labelName&quot;&gt;Online ISSN &lt;/span&gt;&lt;span class=&quot;labelValue&quot;&gt;1559-0089&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span class=&quot;labelName&quot;&gt;Print ISSN &lt;/span&gt;&lt;span class=&quot;labelValue&quot;&gt;1539-2791&lt;/span&gt;&lt;/li&gt;
	&lt;/ul&gt;
&lt;/ul&gt;</description>
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