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  <title>NITRC News Group Forum: prediction-of-post-earthquake-depressive-and-anxiety-symptoms--a-longitudinal-resting-state-fmri-study.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=4372</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=25236674&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Prediction of post-earthquake depressive and anxiety symptoms: a longitudinal resting-state fMRI study.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Sci Rep. 2014;4:6423&lt;/p&gt;
        &lt;p&gt;Authors:  Long J, Huang X, Liao Y, Hu X, Hu J, Lui S, Zhang R, Li Y, Gong Q&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        Neurobiological markers of stress symptom progression for healthy survivors from a disaster (e.g., an earthquake) would greatly help with early intervention to prevent the development of stress-related disorders. However, the relationship between the neurobiological alterations and the symptom progression over time is unclear. Here, we examined 44 healthy survivors of the Wenchuan earthquake in China in a longitudinal resting-state fMRI study to observe the alterations of brain functions related to depressive or anxiety symptom progression. Using multi-variate pattern analysis to the fMRI data, we successfully predicted the depressive or anxiety symptom severity for these survivors in short- (25 days) and long-term (2 years) and the symptom severity changes over time. Several brain areas (e.g., the frontolimbic and striatal areas) and the functional connectivities located within the fronto-striato-thalamic and default-mode networks were found to be correlated with the symptom progression and might play important roles in the adaptation to trauma. &lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 25236674 [PubMed - in process]&lt;/p&gt;
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