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  <title>NITRC News Group Forum: ica-aroma--a-robust-ica-based-strategy-for-removing-motion-artifacts-from-fmri-data.</title>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;ICA-AROMA: A robust ICA-based strategy for removing motion artifacts from fMRI data.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Neuroimage. 2015 Mar 11;&lt;/p&gt;
        &lt;p&gt;Authors:  Pruim RH, Mennes M, van Rooij D, Llera A, Buitelaar JK, Beckmann CF&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        Head motion during functional MRI (fMRI) scanning can induce spurious findings and/or harm detection of true effects. Solutions have been proposed, including deleting ('scrubbing') or regressing out ('spike regression') motion volumes from fMRI time-series. These strategies remove motion-induced signal variations at the cost of destroying the autocorrelation structure of the fMRI time-series and reducing temporal degrees of freedom. ICA-based fMRI denoising strategies overcome these drawbacks but typically require re-training of a classifier, needing manual labeling of derived components (e.g. ICA-FIX; [42]). Here, we propose an ICA-based strategy for Automatic Removal Of Motion Artifacts (ICA-AROMA) that uses a small (n=4), but robust set of theoretically motivated temporal and spatial features. Our strategy does not require classifier re-training, retains the data's autocorrelation structure and largely preserves temporal degrees of freedom. We describe ICA-AROMA, its implementation, and initial validation. ICA-AROMA identified motion components with high accuracy and robustness as illustrated by leave-N-out cross-validation. We additionally validated ICA-AROMA in resting-state (100 participants) and task-based fMRI data (118 participants). Our approach removed (motion-related) spurious noise from both rfMRI and task-based fMRI data to larger extent than regression using 24 motion parameters or spike regression. Furthermore, ICA-AROMA increased sensitivity to group-level activation. Our results show that ICA-AROMA effectively reduces motion-induced signal variations in fMRI data, is applicable across datasets without requiring classifier re-training, and preserves the temporal characteristics of the fMRI data.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 25770991 [PubMed - as supplied by publisher]&lt;/p&gt;
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