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  <title>NITRC News Group Forum: integration-of-multimodal-neuroimaging-methods--a-rationale-for-clinical-applications-of-simultaneous-eeg-fmri.</title>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Integration of multimodal neuroimaging methods: a rationale for clinical applications of simultaneous EEG-fMRI.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Funct Neurol. 2015 Apr 1;:1-12&lt;/p&gt;
        &lt;p&gt;Authors:  Vitali P, Di Ferri C, Vaudano AE, Meletti S, Villani F&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        Functional magnetic resonance imaging (fMRI), which has high spatial resolution, is increasingly used to evaluate cerebral functions in neurological and psychiatric diseases. The main limitation of fMRI is that it detects neural activity indirectly, through the associated slow hemodynamic variations. Because neurovascular coupling can be regionally altered by pathological conditions or drugs, fMRI responses may not truly reflect neural activity. Electroencephalography (EEG) recordings, which directly detect neural activity with optimal temporal resolution, can now be obtained during fMRI data acquisition. Therefore, there is a growing interest in combining the techniques to obtain simultaneous EEG-fMRI recordings. The EEG-fMRI approach has several promising clinical applications. The first is the detection of cortical areas involved in interictal and ictal epileptic activity. Second, combining evoked potentials with fMRI could be an accurate way to study eloquent cortical areas for the planning of neurosurgery or rehabilitation, circumventing the above-mentioned limitation of fMRI. Finally, the use of this approach to evaluate the functional connectivity of resting-state networks would extend the applications of EEG-fMRI to uncooperative or unconscious patients. Integration of multimodal neuroimaging methods: a rationale for clinical applications of simultaneous EEG-fMRI.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 25827588 [PubMed - as supplied by publisher]&lt;/p&gt;
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