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  <title>NITRC News Group Forum: regional-brain-activity-during-jaw-clenching-with-natural-teeth-and-with-occlusal-splints--a-preliminary-functional-mri-study.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=5284</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=26089109&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Regional brain activity during jaw clenching with natural teeth and with occlusal splints: a preliminary functional MRI study.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Cranio. 2015 Jun 19;:2151090315Y0000000017&lt;/p&gt;
        &lt;p&gt;Authors:  Ariji Y, Koyama S, Sakuma S, Nakayama M, Ariji E&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        OBJECTIVE: The purpose of this study was to investigate regional brain activity during jaw clenching with natural teeth and with two types of occlusal splints using functional magnetic resonance imaging (fMRI).&lt;br/&gt;
        METHODS: Sixteen healthy volunteers were enrolled in this study. Blood oxygenation level-dependent (BOLD) fMRI signals were compared under three conditions: during clenching with natural teeth, with a soft splint, and with a hard splint. For each condition, 30-second jaw clenching followed a 60-second rest, and was repeated three times, with intervening 30-second rests. SPM 8 was used for the fMRI analysis.&lt;br/&gt;
        RESULTS: Blood oxygenation level-dependent signals during clenching with natural teeth increased in BA44, 45, and the cerebellum. Blood oxygenation level-dependent signals increased in those areas and in BA17, 18 during clenching with a soft splint. Use of the hard splint increased the BOLD signals in BA6 and BA20, 37 in addition to the areas previously mentioned. Blood oxygenation level-dependent signals in the left BA6, the left BA20, 37, and the right BA44, 45 were significantly higher during clenching with a hard splint than with natural teeth. These regions are associated with motor coordination, memory, and cognition, respectively.&lt;br/&gt;
        CONCLUSION: Jaw clenching with a hard splint caused activity in the widest brain regions, including the associated area with motor coordination.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 26089109 [PubMed - as supplied by publisher]&lt;/p&gt;
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