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  <title>NITRC News Group Forum: interleaved-multishot-imaging-by-spatiotemporal-encoding--a-fast--self-referenced-method-for-high-definition-diffusion-and-functional-mri.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=5312</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=26108165&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Interleaved multishot imaging by spatiotemporal encoding: A fast, self-referenced method for high-definition diffusion and functional MRI.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Magn Reson Med. 2015 Jun 23;&lt;/p&gt;
        &lt;p&gt;Authors:  Schmidt R, Seginer A, Frydman L&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        PURPOSE: Single-shot imaging by spatiotemporal encoding (SPEN) can provide higher immunity to artifacts than its echo planar imaging-based counterparts. Further improvements in resolution and signal-to-noise ratio could be made by rescinding the sequence's single-scan nature. To explore this option, an interleaved SPEN version was developed that was capable of delivering optimized images due to its use of a referenceless correction algorithm.&lt;br/&gt;
        METHODS: A characteristic element of SPEN encoding is the absence of aliasing when its signals are undersampled along the low-bandwidth dimension. This feature was exploited in this study to segment a SPEN experiment into a number of interleaved shots whose inaccuracies were automatically compared and corrected as part of a navigator-free image reconstruction analysis. This could account for normal phase noises, as well as for object motions during the signal collection.&lt;br/&gt;
        RESULTS: The ensuing interleaved SPEN method was applied to phantoms and human volunteers and delivered high-quality images even in inhomogeneous or mobile environments. Submillimeter functional MRI activation maps confined to gray matter regions as well as submillimeter diffusion coefficient maps of human brains were obtained.&lt;br/&gt;
        CONCLUSION: We have developed an interleaved SPEN approach for the acquisition of high-definition images that promises a wider range of functional and diffusion MRI applications even in challenging environments. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 26108165 [PubMed - as supplied by publisher]&lt;/p&gt;
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