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  <title>NITRC News Group Forum: machine-learning-algorithm-accurately-detects-fmri-signature-of-vulnerability-to-major-depression.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=5374</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=26187550&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Machine learning algorithm accurately detects fMRI signature of vulnerability to major depression.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Psychiatry Res. 2015 Jul 5;&lt;/p&gt;
        &lt;p&gt;Authors:  Sato JR, Moll J, Green S, Deakin JF, Thomaz CE, Zahn R&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        Standard functional magnetic resonance imaging (fMRI) analyses cannot assess the potential of a neuroimaging signature as a biomarker to predict individual vulnerability to major depression (MD). Here, we use machine learning for the first time to address this question. Using a recently identified neural signature of guilt-selective functional disconnection, the classification algorithm was able to distinguish remitted MD from control participants with 78.3% accuracy. This demonstrates the high potential of our fMRI signature as a biomarker of MD vulnerability.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 26187550 [PubMed - as supplied by publisher]&lt;/p&gt;
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