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  <title>NITRC News Group Forum: emotion-processing-in-treatment-resistant-schizophrenia-patients-treated-with-clozapine--an-fmri-study.</title>
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        &lt;p&gt;&lt;b&gt;Emotion processing in treatment-resistant schizophrenia patients treated with clozapine: An fMRI study.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Schizophr Res. 2015 Aug 5;&lt;/p&gt;
        &lt;p&gt;Authors:  Potvin S, Tikàsz A, Lungu O, Dumais A, Stip E, Mendrek A&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        OBJECTIVES: To examine the neural correlates of emotion processing in treatment-resistant patients with schizophrenia (SCZ-TR).&lt;br/&gt;
        METHODS: Twenty-two SCZ-TR patients on clozapine, 24 schizophrenia patients on antipsychotics other than clozapine, and 39 healthy controls were scanned using functional neuroimaging while viewing positive, negative and neutral images.&lt;br/&gt;
        RESULTS: Emotionally-laden images (positive and negative) elicited hyper-activations in the dorso-medial prefrontal cortex and left cerebellum in SCZ-TR patients, compared to the two other groups. Similarly, neutral images prompted hyper-activations in the cingulate gyrus in SCZ-TR patients, relative to the two other groups.&lt;br/&gt;
        CONCLUSIONS: Treatment resistance is associated with neuro-functional hyper-activations in schizophrenia patients during emotion processing.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 26255082 [PubMed - as supplied by publisher]&lt;/p&gt;
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