http://www.nitrc.org/forum/forum.php?forum_id=5511 <table border="0" width="100%"><tr><td align="left"/><td align="right"><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;cmd=Link&amp;LinkName=pubmed_pubmed&amp;from_uid=26327319">Related Articles</a></td></tr></table> <p><b>Multi-Subject fMRI Analysis via Combined Independent Component Analysis and Shift-Invariant Canonical Polyadic Decomposition.</b></p> <p>J Neurosci Methods. 2015 Aug 28;</p> <p>Authors: Kuang LD, Lin QH, Gong XF, Cong F, Sui J, Calhoun VD</p> <p>Abstract<br/> BACKGROUND: Canonical polyadic decomposition (CPD) may face a local optimal problem when analyzing multi-subject fMRI data with inter-subject variability. Beckmann and Smith proposed a tensor PICA approach that incorporated an independence constraint to the spatial modality by combining CPD with ICA, and alleviated the problem of inter-subject spatial map (SM) variability.<br/> NEW METHOD: This study extends tensor PICA to incorporate additional inter-subject time course (TC) variability and to connect CPD and ICA in a new way. Assuming multiple subjects share common TCs but with different time delays, we accommodate subject-dependent TC delays into the CP model based on the idea of shift-invariant CP (SCP). We use ICA as an initialization step to provide the aggregating mixing matrix for shift-invariant CPD to estimate shared TCs with subject-dependent delays and intensities. We then estimate shared SMs using a least-squares fit post shift-invariant CPD.<br/> RESULTS: Using simulated fMRI data as well as actual fMRI data we demonstrate that the proposed approach improves the estimates of the shared SMs and TCs, and the subject-dependent TC delays and intensities. The default mode component illustrates larger TC delays than the task-related component.<br/> COMPARISON WITH EXISTING METHOD(S): The proposed approach shows improvements over tensor PICA in particular when TC delays are large, and also outperforms SCP with SM orthogonality constraint and SCP with ICA-based SM initialization.<br/> CONCLUSIONS: TCs with subject-dependent delays conform to the true situation of multi-subject fMRI data. The proposed approach is suitable for decomposing multi-subject fMRI data with large inter-subject temporal and spatial variability.<br/> </p><p>PMID: 26327319 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Sun, 03 May 2026 10:52:09 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator