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  <title>NITRC News Group Forum: compressed-sensing-for-fmri--feasibility-study-on-the-acceleration-of-non-epi-fmri-at-9.4t.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=5600</link>
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        &lt;p&gt;&lt;b&gt;Compressed Sensing for fMRI: Feasibility Study on the Acceleration of Non-EPI fMRI at 9.4T.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Biomed Res Int. 2015;2015:131926&lt;/p&gt;
        &lt;p&gt;Authors:  Han PK, Park SH, Kim SG, Ye JC&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        Conventional functional magnetic resonance imaging (fMRI) technique known as gradient-recalled echo (GRE) echo-planar imaging (EPI) is sensitive to image distortion and degradation caused by local magnetic field inhomogeneity at high magnetic fields. Non-EPI sequences such as spoiled gradient echo and balanced steady-state free precession (bSSFP) have been proposed as an alternative high-resolution fMRI technique; however, the temporal resolution of these sequences is lower than the typically used GRE-EPI fMRI. One potential approach to improve the temporal resolution is to use compressed sensing (CS). In this study, we tested the feasibility of k-t FOCUSS-one of the high performance CS algorithms for dynamic MRI-for non-EPI fMRI at 9.4T using the model of rat somatosensory stimulation. To optimize the performance of CS reconstruction, different sampling patterns and k-t FOCUSS variations were investigated. Experimental results show that an optimized k-t FOCUSS algorithm with acceleration by a factor of 4 works well for non-EPI fMRI at high field under various statistical criteria, which confirms that a combination of CS and a non-EPI sequence may be a good solution for high-resolution fMRI at high fields.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 26413503 [PubMed - as supplied by publisher]&lt;/p&gt;
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