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  <title>NITRC News Group Forum: cue-reactivity-in-experienced-electronic-cigarette-users--novel-stimulus-videos-and-a-pilot-fmri-study.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=5663</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=26478134&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Cue-reactivity in experienced electronic cigarette users: Novel stimulus videos and a pilot fMRI study.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Brain Res Bull. 2015 Oct 15;&lt;/p&gt;
        &lt;p&gt;Authors:  Nichols TT, Foulds J, Yingst J, Veldheer S, Hrabovsky S, Richie J, Eissenberg T, Wilson SJ&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        Some individuals who try electronic cigarettes (e-cigarettes) continue to use long-term. Previous research has investigated the safety of e-cigarettes and their potential for use in smoking cessation, but comparatively little research has explored chronic or habitual e-cigarette use. In particular, the relationship between e-cigarette cues and craving is unknown. We sought to bridge this gap by developing a novel set of e-cigarette (salient) and electronic toothbrush (neutral) videos for use in cue-reactivity paradigms. Additionally, we demonstrate the utility of this approach in a pilot fMRI study of 7 experienced e-cigarette users. Participants were scanned while viewing the cue videos before and after 10min use of their own e-cigarettes (producing an 11.7 ng/ml increase in plasma nicotine concentration). A significant session (pre- and post-use) by video type (salient and neutral) interaction was exhibited in many sensorimotor areas commonly activated in other cue-reactivity paradigms. We did not detect significant cue-related activity in other brain regions notable in the craving literature. Possible reasons for this discrepancy are discussed, including the importance of matching cue stimuli to participants' experiences.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 26478134 [PubMed - as supplied by publisher]&lt;/p&gt;
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