http://www.nitrc.org/forum/forum.php?forum_id=5835 <table border="0" width="100%"><tr><td align="left"/></tr></table> <p><b>Improving Motor Corticothalamic Communication After Stroke Using Real-Time fMRI Connectivity-Based Neurofeedback.</b></p> <p>Neurorehabil Neural Repair. 2015 Dec 14;</p> <p>Authors: Liew SL, Rana M, Cornelsen S, Fortunato de Barros Filho M, Birbaumer N, Sitaram R, Cohen LG, Soekadar SR</p> <p>Abstract<br/> BACKGROUND: Two thirds of stroke survivors experience motor impairment resulting in long-term disability. The anatomical substrate is often the disruption of cortico-subcortical pathways. It has been proposed that reestablishment of cortico-subcortical communication relates to functional recovery.<br/> OBJECTIVE: In this study, we applied a novel training protocol to augment ipsilesional cortico-subcortical connectivity after stroke. Chronic stroke patients with severe motor impairment were provided online feedback of blood-oxygenation level dependent signal connectivity between cortical and subcortical regions critical for motor function using real-time functional magnetic resonance imaging neurofeedback.<br/> RESULTS: In this proof of principle study, 3 out of 4 patients learned to voluntarily modulate cortico-subcortical connectivity as intended.<br/> CONCLUSIONS: Our results document for the first time the feasibility and safety for patients with chronic stroke and severe motor impairment to self-regulate and augment ipsilesional cortico-subcortical connectivity through neurofeedback using real-time functional magnetic resonance imaging.<br/> </p><p>PMID: 26671217 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Mon, 04 May 2026 13:02:11 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator