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  <title>NITRC News Group Forum: identifying-activation-centers-with-spatial-cox-point-processes-using-fmri-data.</title>
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        &lt;p&gt;&lt;b&gt;Identifying Activation Centers with Spatial Cox Point Processes Using FMRI Data.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;IEEE/ACM Trans Comput Biol Bioinform. 2015 Dec 17;&lt;/p&gt;
        &lt;p&gt;Authors:  Ray M, Kang J, Zhang H&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        We developed a Bayesian clustering method to identify significant regions of brain activation. Coordinate-based meta data originating from functional magnetic resonance imaging (fMRI) were of primary interest. Individual fMRI has the ability to measure the intensity of blood flow and oxygen to a location within the brain that was activated by a given thought or emotion. The proposed method performed clustering on two levels, latent foci center and study activation center, with a spatial Cox point process utilizing the Dirichlet process to describe the distribution of foci. Intensity was modeled as a function of distance between the focus and the center of the cluster of foci using a Gaussian kernel. Simulation studies were conducted to evaluate the sensitivity and robustness of the method with respect to cluster identification and underlying data distributions. We applied the method to a meta data set to identify emotion foci centers.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 26701895 [PubMed - as supplied by publisher]&lt;/p&gt;
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