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  <title>NITRC News Group Forum: coil-to-coil-physiological-noise-correlations-and-their-impact-on-functional-mri-time-series-signal-to-noise-ratio.</title>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Coil-to-coil physiological noise correlations and their impact on functional MRI time-series signal-to-noise ratio.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Magn Reson Med. 2016 Jan 12;&lt;/p&gt;
        &lt;p&gt;Authors:  Triantafyllou C, Polimeni JR, Keil B, Wald LL&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        PURPOSE: Physiological nuisance fluctuations (&quot;physiological noise&quot;) are a major contribution to the time-series signal-to-noise ratio (tSNR) of functional imaging. While thermal noise correlations between array coil elements have a well-characterized effect on the image Signal to Noise Ratio (SNR0 ), the element-to-element covariance matrix of the time-series fluctuations has not yet been analyzed. We examine this effect with a goal of ultimately improving the combination of multichannel array data.&lt;br/&gt;
        THEORY AND METHODS: We extend the theoretical relationship between tSNR and SNR0 to include a time-series noise covariance matrix Ψt , distinct from the thermal noise covariance matrix Ψ0 , and compare its structure to Ψ0 and the signal coupling matrix SS(H) formed from the signal intensity vectors S.&lt;br/&gt;
        RESULTS: Inclusion of the measured time-series noise covariance matrix into the model relating tSNR and SNR0 improves the fit of experimental multichannel data and is shown to be distinct from Ψ0 or SS(H) .&lt;br/&gt;
        CONCLUSION: Time-series noise covariances in array coils are found to differ from Ψ0 and more surprisingly, from the signal coupling matrix SS(H) . Correct characterization of the time-series noise has implications for the analysis of time-series data and for improving the coil element combination process. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 26756964 [PubMed - as supplied by publisher]&lt;/p&gt;
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