http://www.nitrc.org/forum/forum.php?forum_id=5923 <table border="0" width="100%"><tr><td align="left"/></tr></table> <p><b>Resting-State Blood Oxygen Level-Dependent Functional MRI: A Paradigm Shift in Preoperative Brain Mapping.</b></p> <p>Stereotact Funct Neurosurg. 2016 Jan 20;93(6):427-439</p> <p>Authors: Leuthardt EC, Allen M, Kamran M, Hawasli AH, Snyder AZ, Hacker CD, Mitchell TJ, Shimony JS</p> <p>Abstract<br/> Currently, functional magnetic resonance imaging (fMRI) facilitates a preoperative awareness of an association of an eloquent region with a tumor. This information gives the neurosurgeon helpful information that can aid in creating a surgical strategy. Typically, task-based fMRI has been employed to preoperatively localize speech and motor function. Task-based fMRI depends on the patient's ability to comply with the task paradigm, which often is impaired in the setting of a brain tumor. This problem is overcome by using resting-state fMRI (rs-fMRI) to localize function. rs-fMRI measures spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, representing the brain's functional organization. In a neurosurgical context, it allows noninvasive simultaneous assessment of multiple large-scale distributed networks. Compared with task-related fMRI, rs-fMRI provides more comprehensive information on the functional architecture of the brain and is applicable in settings where task-related fMRI may provide inadequate information or could not be performed. Taken together, rs-fMRI substantially expands the preoperative mapping capability in efficiency, effectiveness, and scope. In this article, a brief introduction into rs-fMRI processing methods is followed by a detailed discussion on the role rs-fMRI plays in presurgical planning.<br/> </p><p>PMID: 26784290 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Mon, 04 May 2026 1:41:32 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator