http://www.nitrc.org/forum/forum.php?forum_id=5948 <table border="0" width="100%"><tr><td align="left"/></tr></table> <p><b>Enhancement of functional MRI signal at high-susceptibility regions of brain using simultaneous multiecho multithin-slice summation imaging technique.</b></p> <p>J Magn Reson Imaging. 2016 Jan 28;</p> <p>Authors: Kim T, Zhao T, Bae KT</p> <p>Abstract<br/> PURPOSE: To increase temporal-signal-to-noise ratio (tSNR) and blood oxygen level-dependent (BOLD) sensitivity at high-susceptibility regions of the brain by means of a simultaneous multiecho multithin-slice summation imaging technique.<br/> MATERIALS AND METHODS: The simultaneous multislice (SMS) technique was implemented with multiecho (SMSME) and multiecho with thin-slice summation (SMSME-thin) at 3T. Multiecho data were summated based on the local apparent T2* weighting factor. Ten healthy subjects were studied for the whole brain activation by breath-holding. The tSNR values and the number of activated pixels acquired with SMSME and SMSME-thin were compared with those acquired with the conventional gradient-echo EPI in multiple brain regions RESULTS: SMS methods accelerated imaging time by 5-fold as compared with the conventional method, resulting in the acquisition of three echoes and four thin-slices during the same TR of 2.5 seconds. At high-susceptibility regions, including the amygdala, inferior and middle temporal, and anterior frontal lobes, SMSME increased tSNR values by up to ∼80% and BOLD activation by up to ∼20% (paired t-test, P &lt; 0.05). SMSME-thin further increased values as compared with SMSME (∼45% for tSNR and ∼20% for activation, P &lt; 0.05).<br/> CONCLUSION: The SMSME-thin imaging technique enhanced the temporal-signal-to-noise ratio and functional activation at high susceptibility regions of the brain. J. Magn. Reson. Imaging 2016.<br/> </p><p>PMID: 26821385 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Mon, 04 May 2026 5:58:11 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator