http://www.nitrc.org/forum/forum.php?forum_id=5985 <table border="0" width="100%"><tr><td align="left"/></tr></table> <p><b>Sensory and optogenetically driven single-vessel fMRI.</b></p> <p>Nat Methods. 2016 Feb 8;</p> <p>Authors: Yu X, He Y, Wang M, Merkle H, Dodd SJ, Silva AC, Koretsky AP</p> <p>Abstract<br/> Magnetic resonance imaging (MRI) sensitivity approaches vessel specificity. We developed a single-vessel functional MRI (fMRI) method to image the contribution of vascular components to blood oxygenation level-dependent (BOLD) and cerebral blood volume (CBV) fMRI signal. We mapped individual vessels penetrating the rat somatosensory cortex with 100-ms temporal resolution by MRI with sensory or optogenetic stimulation. The BOLD signal originated primarily from venules, and the CBV signal from arterioles. The single-vessel fMRI method and its combination with optogenetics provide a platform for mapping the hemodynamic signal through the neurovascular network with specificity at the level of individual arterioles and venules.<br/> </p><p>PMID: 26855362 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Mon, 04 May 2026 13:30:10 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator