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  <title>NITRC News Group Forum: an-initial-fmri-study-on-neural-correlates-of-prayer-in-members-of-alcoholics-anonymous.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=6100</link>
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        &lt;p&gt;&lt;b&gt;An initial fMRI study on neural correlates of prayer in members of Alcoholics Anonymous.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Am J Drug Alcohol Abuse. 2016 Mar 25;:1-11&lt;/p&gt;
        &lt;p&gt;Authors:  Galanter M, Josipovic Z, Dermatis H, Weber J, Millard MA&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        BACKGROUND: Many individuals with alcohol-use disorders who had experienced alcohol craving before joining Alcoholics Anonymous (AA) report little or no craving after becoming long-term members. Their use of AA prayers may contribute to this. Neural mechanisms underlying this process have not been delineated.&lt;br/&gt;
        OBJECTIVE: To define experiential and neural correlates of diminished alcohol craving following AA prayers among members with long-term abstinence.&lt;br/&gt;
        METHODS: Twenty AA members with long-term abstinence participated. Self-report measures and functional magnetic resonance imaging of differential neural response to alcohol-craving-inducing images were obtained in three conditions: after reading of AA prayers, after reading irrelevant news, and with passive viewing. Random-effects robust regressions were computed for the main effect (prayer &amp;gt; passive + news) and for estimating the correlations between the main effect and the self-report measures.&lt;br/&gt;
        RESULTS: Compared to the other two conditions, the prayer condition was characterized by: less self-reported craving; increased activation in left-anterior middle frontal gyrus, left superior parietal lobule, bilateral precuneus, and bilateral posterior middle temporal gyrus. Craving following prayer was inversely correlated with activation in brain areas associated with self-referential processing and the default mode network, and with characteristics reflecting AA program involvement.&lt;br/&gt;
        CONCLUSION: AA members' prayer was associated with a relative reduction in self-reported craving and with concomitant engagement of neural mechanisms that reflect control of attention and emotion. These findings suggest neural processes underlying the apparent effectiveness of AA prayer.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 27015258 [PubMed - as supplied by publisher]&lt;/p&gt;
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