http://www.nitrc.org/forum/forum.php?forum_id=6180 <table border="0" width="100%"><tr><td align="left"/></tr></table> <p><b>Infiltration of the basal ganglia by brain tumors is associated with the development of co-dominant language function on fMRI.</b></p> <p>Brain Lang. 2016 Apr 21;155-156:44-48</p> <p>Authors: Shaw K, Brennan N, Woo K, Zhang Z, Young R, Peck K, Holodny A</p> <p>Abstract<br/> Studies have shown that some patients with left-hemispheric brain tumors have an increased propensity for developing right-sided language support. However, the precise trigger for establishing co-dominant language function in brain tumor patients remains unknown. We analyzed the MR scans of patients with left-hemispheric tumors and either co-dominant (n=35) or left-hemisphere dominant (n=35) language function on fMRI to investigate anatomical factors influencing hemispheric language dominance. Of eleven neuroanatomical areas evaluated for tumor involvement, the basal ganglia was significantly correlated with co-dominant language function (p&lt;0.001). Moreover, among patients whose tumors invaded the basal ganglia, those with language co-dominance performed significantly better on the Boston Naming Test, a clinical measure of aphasia, compared to their left-lateralized counterparts (56.5 versus 36.5, p=0.025). While further studies are needed to elucidate the role of the basal ganglia in establishing co-dominance, our results suggest that reactive co-dominance may afford a behavioral advantage to patients with left-hemispheric tumors.<br/> </p><p>PMID: 27108246 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Tue, 05 May 2026 1:09:05 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator