http://www.nitrc.org/forum/forum.php?forum_id=6287 <table border="0" width="100%"><tr><td align="left"/><td align="right"><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;cmd=Link&amp;LinkName=pubmed_pubmed&amp;from_uid=27227967">Related Articles</a></td></tr></table> <p><b>Betel quid chewing alters functional connectivity in frontal and default networks: A resting-state fMRI study.</b></p> <p>J Magn Reson Imaging. 2016 May 26;</p> <p>Authors: Huang X, Liu Z, Mwansisya TE, Pu W, Zhou L, Liu C, Chen X, Rohrbaugh R, Marienfeld C, Xue Z, Liu H</p> <p>Abstract<br/> PURPOSE: To explore the acute effect of betel quid (BQ) use on functional network connectivity by comparing the global functional brain networks and their subsets before and immediately after BQ chewing.<br/> MATERIALS AND METHODS: Resting-state functional magnetic resonance imaging (fMRI) was performed in 27 healthy male participants before and just after chewing BQ on a 3.0T scanner with a gradient-echo echo planar imaging sequence. Independent component analysis (ICA) was used to determine components that represent the brain's functional networks and their spatial aspects of functional connectivity. A paired t-test was used for exploring the connectivity differences in each network before and after BQ chewing.<br/> RESULTS: Sixteen networks were identified by ICA. Nine of them showed connectivity differences before and after BQ chewing (P &lt; 0.05 false discovery rate corrected): (A) orbitofrontal, (B) left frontoparietal, (C) visual, (D) right frontoparietal, (E) anterior default mode, (F) medial frontal/anterior cingulate (G) frontotemporal, (H) occipital/parietal, (I) occipital/temporal/cerebellum. Moreover, networks A, B, C, D, G, H, and I showed increased connectivity, while networks E and F showed decreased connectivity in participants after BQ chewing compared to before chewing.<br/> CONCLUSION: The acute effects of BQ use appear to actively alter functional connectivity of frontal and default networks that are known to play a key role in addictive behavior. J. Magn. Reson. Imaging 2016.<br/> </p><p>PMID: 27227967 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Mon, 04 May 2026 21:33:35 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator