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  <title>NITRC News Group Forum: influences-of-head-motion-regression-on-high-frequency-oscillation-amplitudes-of-resting-state-fmri-signals.</title>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Influences of Head Motion Regression on High-Frequency Oscillation Amplitudes of Resting-State fMRI Signals.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Front Hum Neurosci. 2016;10:243&lt;/p&gt;
        &lt;p&gt;Authors:  Yuan BK, Zang YF, Liu DQ&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        High-frequency oscillations (HFOs, &amp;gt;0.1 Hz) of resting-state fMRI (rs-fMRI) signals have received much attention in recent years. Denoising is critical for HFO studies. Previous work indicated that head motion (HM) has remarkable influences on a variety of rs-fMRI metrics, but its influences on rs-fMRI HFOs are still unknown. In this study, we investigated the impacts of HM regression (HMR) on HFO results using a fast sampling rs-fMRI dataset. We demonstrated that apparent high-frequency (∼0.2-0.4 Hz) components existed in the HM trajectories in almost all subjects. In addition, we found that individual-level HMR could robustly reveal more between-condition (eye-open vs. eye-closed) amplitude differences in high-frequency bands. Although regression of mean framewise displacement (FD) at the group level had little impact on the results, mean FD could significantly account for inter-subject variance of HFOs even after individual-level HMR. Our findings suggest that HM artifacts should not be ignored in HFO studies, and HMR is necessary for detecting HFO between-condition differences. &lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 27303280 [PubMed]&lt;/p&gt;
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