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  <title>NITRC News Group Forum: marker-based-ballistocardiographic-artifact-correction-improves-spike-identification-in-eeg-fmri-of-focal-epilepsy-patients.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=6408</link>
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        &lt;p&gt;&lt;b&gt;Marker-based ballistocardiographic artifact correction improves spike identification in EEG-fMRI of focal epilepsy patients.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Clin Neurophysiol. 2016 Jun 8;127(8):2802-2811&lt;/p&gt;
        &lt;p&gt;Authors:  Körbl K, Jacobs J, Herbst M, Zaitsev M, Schulze-Bonhage A, Hennig J, LeVan P&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        OBJECTIVES: Ballistocardiographic (BCG) artifacts resemble interictal epileptic discharges (IEDs) and can lead to incorrect IED identification in EEG-fMRI. This study investigates IEDs marked in EEGs corrected using information from a moiré phase tracking (MPT) marker.&lt;br/&gt;
        METHODS: EEG-fMRI from 18 patients was processed with conventional methods for BCG removal, while 9 patients used a MPT marker. IEDs were marked first without ECG information. In a second review, suspicious IEDs synchronous with the BCG were discarded. After each review, an event-related fMRI analysis was performed on the marked IEDs.&lt;br/&gt;
        RESULTS: No difference was found in the proportion of suspicious IEDs in the 2 patient groups. However, the distribution of IED timings was significantly related to the cardiac cycle in 11 of 18 patients recorded without MPT marker, but only 2 of 9 patients with marker. In patients recorded without marker, failing to discard suspicious IEDs led to more inaccurate fMRI maps and more distant activations.&lt;br/&gt;
        CONCLUSIONS: BCG artifact correction based on MPT recordings allowed a more straightforward identification of IEDs that did not require ECG information in the large majority of patients.&lt;br/&gt;
        SIGNIFICANCE: Marker-based ballistocardiographic artifact correction greatly facilitates the study of the generators of interictal discharges with EEG-fMRI.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 27417056 [PubMed - as supplied by publisher]&lt;/p&gt;
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