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  <title>NITRC News Group Forum: population-level-correction-of-systematic-motion-artifacts-in-fmri-in-patients-with-ischemic-stroke.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=6830</link>
  <description>
	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=27859975&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Population-Level Correction of Systematic Motion Artifacts in fMRI in Patients with Ischemic Stroke.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;J Neuroimaging. 2016 Nov 17;:&lt;/p&gt;
        &lt;p&gt;Authors:  Aranyi C, Opposits G, Nagy M, Berényi E, Vér C, Csiba L, Katona P, Spisák T, Emri M&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        BACKGROUND: The aim of this study was to reveal potential sources of systematic motion artifacts in stroke functional magnetic resonance imaging (fMRI) focusing on those causing stimulus-correlated motion on the individual-level and separate the motion effect on the fMRI signal changing from the activation-induced alteration at population level.&lt;br/&gt;
        METHODS: Eleven ischemic stroke patients were examined by fMRI. The fMRI paradigm was based on passive ankle movement on both the healthy and the paretic leg's side. Three individual-level motion correction strategies were compared and we introduced five measures to characterize each subjects' in-scanner relative head movement. After analyzing the correlation of motion parameters and the subjects' physiological scale scores, we selected a parameter to model the motion-related artifacts in the second-level analysis.&lt;br/&gt;
        RESULTS: At first (individual) level analysis, the noise-component correction-based CompCor method provided the highest -log10(p) value of cluster-level occurrence probability at 12.4/13.6 for healthy and paretic side stimulus, respectively, with a maximal z-value of 15/16.3. Including the motion parameter at second (group) level resulted in lower cluster occurrence values at 10.9/5.55 while retaining the maximal z-value.&lt;br/&gt;
        CONCLUSIONS: We proposed a postprocessing pipeline for ischemic stroke fMRI data that combine the CompCor correction at first level with the modeling of motion effect at second-level analysis by a parameter obtained from fMRI data. Our solution is applicable for any fMRI-based stroke rehabilitation study since it does not require any MRI-compatible motion capture system and is based on commonly used methods.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 27859975 [PubMed - as supplied by publisher]&lt;/p&gt;
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