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  <title>NITRC News Group Forum: adaptive-independent-vector-analysis-for-multi-subject-complex-valued-fmri-data.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=7157</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=28214528&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Adaptive Independent Vector Analysis for Multi-Subject Complex-Valued fMRI Data.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;J Neurosci Methods. 2017 Feb 15;:&lt;/p&gt;
        &lt;p&gt;Authors:  Kuang LD, Lin QH, Gong XF, Cong F, Calhoun VD&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        BACKGROUND: Complex-valued fMRI data can provide additional insights beyond magnitude-only data. However, independent vector analysis (IVA), which has exhibited great potential for group analysis of magnitude-only fMRI data, has rarely been applied to complex-valued fMRI data. The main challenges in this application include the extremely noisy nature and large variability of the source component vector (SCV) distribution.&lt;br/&gt;
        NEW METHOD: To address these challenges, we propose an adaptive fixed-point IVA algorithm for analyzing multiple-subject complex-valued fMRI data. We exploited a multivariate generalized Gaussian distribution (MGGD)- based nonlinear function to match varying SCV distributions in which the MGGD shape parameter was estimated using maximum likelihood estimation. To achieve our de-noising goal, we updated the MGGD-based nonlinearity in the dominant SCV subspace, and employed a post-IVA de-noising strategy based on phase information in the IVA estimates. We also incorporated the pseudo-covariance matrix of fMRI data into the algorithm to emphasize the noncircularity of complex-valued fMRI sources.&lt;br/&gt;
        RESULTS: from simulated and experimental fMRI data demonstrated the efficacy of our method. Comparison with Existing Method(s) Our approach exhibited significant improvements over typical complex-valued IVA algorithms, especially during higher noise levels and larger spatial and temporal changes. As expected, the proposed complex-valued IVA algorithm detected more contiguous and reasonable activations than the magnitude-only method for task-related (393%) and default mode (301%) spatial maps.&lt;br/&gt;
        CONCLUSIONS: The proposed approach is suitable for decomposing multi-subject complex-valued fMRI data, and has great potential for capturing additional subject variability.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 28214528 [PubMed - as supplied by publisher]&lt;/p&gt;
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