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  <title>NITRC News Group Forum: walnut-consumption-increases-activation-of-the-insula-to-highly-desirable-food-cues--a-randomized--double-blind--placebo-controlled--cross-over-fmri-study.</title>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=28715141&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Walnut consumption increases activation of the insula to highly desirable food cues: A randomized, double-blind, placebo-controlled, cross-over fMRI study.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Diabetes Obes Metab. 2017 Jul 17;:&lt;/p&gt;
        &lt;p&gt;Authors:  Farr OM, Tuccinardi D, Upadhyay J, Oussaada SM, Mantzoros CS&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        AIMS: The use of walnuts is recommended for obesity and type 2 diabetes, although the mechanisms through which walnuts may improve appetite and/or glycemic control remain largely unknown.&lt;br/&gt;
        MATERIALS AND METHODS: To determine whether short-term walnut consumption could alter the neural control of appetite using functional magnetic resonance imaging, we performed a randomized, placebo-controlled, double-blind, cross-over trial of 10 patients who received, while living in the controlled environment of a clinical research center, either walnuts or placebo (using a validated smoothie delivery system) for 5 days each, separated by a wash-out period of one month.&lt;br/&gt;
        RESULTS: Walnut consumption decreased feelings of hunger and appetite assessed using visual analog scales and increased the activation of the right insula to highly desirable food cues.&lt;br/&gt;
        CONCLUSIONS: These findings suggest that walnut consumption may increase salience and cognitive control processing of highly desirable food cues, leading to the beneficial metabolic effects observed. ClinicalTrials.gov: NCT02673281.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 28715141 [PubMed - as supplied by publisher]&lt;/p&gt;
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