http://www.nitrc.org/forum/forum.php?forum_id=7795 <table border="0" width="100%"><tr><td align="left"/></tr></table> <p><b>Self-efficacy modulates the neural correlates of craving in male smokers and ex-smokers: an fMRI study.</b></p> <p>Addict Biol. 2017 Sep 07;:</p> <p>Authors: Ono M, Kochiyama T, Fujino J, Sozu T, Kawada R, Yokoyama N, Sugihara G, Murai T, Takahashi H</p> <p>Abstract<br/> The regulation of cue-induced craving for cigarettes is a key factor in smoking cessation. Outcomes of smoking cessation have been linked to self-efficacy, faith in one's own ability, in smokers. However, no study has examined the neural basis of self-efficacy during the control of craving. We examined whether self-efficacy can affect the neural response to smoking cues in smokers and ex-smokers using functional magnetic resonance imaging. During scanning, participants were instructed (1) to view smoking-related images passively, (2) to view the smoking-related images with a strategy focused on self-efficacy to control cue-induced craving or (3) to view neutral images. In smokers, the self-efficacy strategy significantly reduced self-reported craving. This strategy was related to increased activation in the rostral medial prefrontal cortex (rmPFC) and the pregenual anterior cingulate cortex in smokers compared with ex-smokers. Furthermore, smokers showed increased effective connectivity between rmPFC and hippocampus and between pregenual anterior cingulate cortex and parahippocampus gyrus when employing the self-efficacy strategy compared with ex-smokers. The magnitude of the rmPFC-hippocampus connectivity was positively correlated with self-reported self-efficacy. Our findings suggest that in smokers, self-efficacy is related to activation and connectivity in brain regions involved in regulating craving and self-assessment. The current study provides evidence for understanding the vunderlying cognitive and neurobiological mechanisms involved in the control of craving to smoke cigarettes.<br/> </p><p>PMID: 28881072 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Sun, 03 May 2026 3:23:46 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator