http://www.nitrc.org/forum/forum.php?forum_id=7913 <table border="0" width="100%"><tr><td align="left"/><td align="right"><a href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;cmd=Link&amp;LinkName=pubmed_pubmed&amp;from_uid=29025324">Related Articles</a></td></tr></table> <p><b>The effects of head-cooling on brain function during passive hyperthermia: an fMRI study.</b></p> <p>Int J Hyperthermia. 2017 Oct 12;:1-20</p> <p>Authors: Xue Y, Li L, Qian S, Liu K, Zhou XJ, Li B, Jiang Q, Wu Z, Du L, Sun G</p> <p>Abstract<br/> PURPOSE: To investigate the effect of head-cooling on resting-state spontaneous brain activity during passive hyperthermia.<br/> METHODS: An environmental heat exposure was simulated on 16 healthy men under a normal control condition (NC) at 25°C and two hot conditions at 50°C with (HHC) and without (HOT) keeping the head cool, respectively. Resting-state functional MRI (fMRI) data were acquired under each condition and the values of amplitude low frequency fluctuations (ALFF) and z functional connectivity (zFC) were computed to examine regional activity and functional integration, respectively. Pearson's correlation analysis between the ALFF value and subjective sensations scores were performed.<br/> RESULTS: Brain regions with significant ALFF differences among the three conditions were found primarily in the right medial prefrontal cortex/anterior cingulate cortex (MPFC/ACC), bilateral posterior cingulate cortex/precuneus (PCC/PCu), and right fusiform gyrus. Compared to the NC or HOT condition, the HHC condition exhibited significantly increased ALFF in the bilateral PCC/PCu and decreased ALFF in the right fusiform gyrus. However, ALFF of the right MPFC/ACC showed no significant difference between the NC and HHC conditions. Positive FC between the right MPFC/ACC and bilateral PCC/PCu was significantly increased in HHC condition with respect to HOT condition. Negative FC between the right fusiform gyrus and the right MPFC/ACC, bilateral PCC/PCu was observed with a decreasing trend from the HHC condition to the HOT condition. Moreover, head-cooling also improved thermal comfort during passive hyperthermia.<br/> CONCLUSIONS: Head-cooling could substantially reduce the negative effect of hyperthermia on human brain activity as well as thermal sensation.<br/> </p><p>PMID: 29025324 [PubMed - as supplied by publisher]</p> en-us Copyright 2000-2026 NITRC OSI Sun, 03 May 2026 7:04:09 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator