http://www.nitrc.org/forum/forum.php?forum_id=8253 <table border="0" width="100%"><tr><td align="left"/></tr></table> <p><b>Human brain functional areas of unitary pooled activity discovered with fMRI.</b></p> <p>Sci Rep. 2018 Feb 05;8(1):2388</p> <p>Authors: Huang J</p> <p>Abstract<br/> We report the discovery of human brain functional areas of unitary pooled activity (FAUPAs) using fMRI. A FAUPA is defined as an area in which the temporal variation of the activity is the same across the entire area. This dynamically unitary activity implies a perfect temporal correlation everywhere within the FAUPA for the activity-induced BOLD response, i.e., the corresponding Pearson correlation coefficient (R) is 1 for the BOLD responses of any two locations within the FAUPA. A novel method was developed to identify the FAUPA. In this study, nine subjects had a resting-state (rs) fMRI and a task-fMRI. FAUPAs have been identified for both rs- and task-fMRI, and their determination was objective and automatic, with no a-priori knowledge. The group mean of R was 0.952 ± 0.004 for the rs-fMRI and 0.950 ± 0.002 for the task-fMRI, showing the dynamically unitary activity within each FAUPA. For the finger-tapping (FT) task, the group-mean BOLD signal time course of the FT-associated FAUPAs in the primary motor cortex was almost perfectly correlated with the FT-induced ideal response (R = 0.9330, P = 1.8 × 10-56), confirming the association of the FAUPA with the task. A task-associated FAUPA may play the role of a functional unit for a particular neural computation.<br/> </p><p>PMID: 29403027 [PubMed - in process]</p> en-us Copyright 2000-2026 NITRC OSI Fri, 01 May 2026 0:53:31 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator