http://www.nitrc.org/forum/forum.php?forum_id=8549 <table border="0" width="100%"><tr><td align="left"/><td align="right"><a href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;cmd=Link&amp;LinkName=pubmed_pubmed&amp;from_uid=29712947">Related Articles</a></td></tr></table> <p><b>Resting-state fMRI study of brain activation using low-intensity repetitive transcranial magnetic stimulation in rats.</b></p> <p>Sci Rep. 2018 Apr 30;8(1):6706</p> <p>Authors: Seewoo BJ, Feindel KW, Etherington SJ, Rodger J</p> <p>Abstract<br/> Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technique used to treat many neuropsychiatric conditions. However, the mechanisms underlying its mode of action are still unclear. This is the first rodent study using resting-state functional MRI (rs-fMRI) to examine low-intensity (LI) rTMS effects, in an effort to provide a direct means of comparison between rodent and human studies. Using anaesthetised Sprague-Dawley rats, rs-fMRI data were acquired before and after control or LI-rTMS at 1 Hz, 10 Hz, continuous theta burst stimulation (cTBS) or biomimetic high-frequency stimulation (BHFS). Independent component analysis revealed LI-rTMS-induced changes in the resting-state networks (RSN): (i) in the somatosensory cortex, the synchrony of resting activity decreased ipsilaterally following 10 Hz and bilaterally following 1 Hz stimulation and BHFS, and increased ipsilaterally following cTBS; (ii) the motor cortex showed bilateral changes following 1 Hz and 10 Hz stimulation, a contralateral decrease in synchrony following BHFS, and an ipsilateral increase following cTBS; and (iii) hippocampal synchrony decreased ipsilaterally following 10 Hz, and bilaterally following 1 Hz stimulation and BHFS. The present findings demonstrate that LI-rTMS modulates functional links within the rat RSN with frequency-specific outcomes, and the observed changes are similar to those described in humans following rTMS.<br/> </p><p>PMID: 29712947 [PubMed - in process]</p> en-us Copyright 2000-2026 NITRC OSI Tue, 28 Apr 2026 14:04:20 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator