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  <title>NITRC News Group Forum: segan--adversarial-network-with-multi-scale-l-1-loss-for-medical-image-segmentation</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=8552</link>
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                  &lt;h3 class=&quot;a-plus-plus&quot;&gt;Abstract&lt;/h3&gt;
                  &lt;p class=&quot;a-plus-plus&quot;&gt;Inspired by classic Generative Adversarial Networks (GANs), we propose a novel end-to-end adversarial neural network, called SegAN, for the task of medical image segmentation. Since image segmentation requires dense, pixel-level labeling, the single scalar real/fake output of a classic GAN’s discriminator may be ineffective in producing stable and sufficient gradient feedback to the networks. Instead, we use a fully convolutional neural network as the segmentor to generate segmentation label maps, and propose a novel adversarial critic network with a multi-scale &lt;em class=&quot;a-plus-plus&quot;&gt;L&lt;/em&gt;&lt;sub class=&quot;a-plus-plus&quot;&gt;1&lt;/sub&gt; loss function to force the critic and segmentor to learn both global and local features that capture long- and short-range spatial relationships between pixels. In our SegAN framework, the segmentor and critic networks are trained in an alternating fashion in a min-max game: The critic is trained by maximizing a multi-scale loss function, while the segmentor is trained with only gradients passed along by the critic, with the aim to minimize the multi-scale loss function. We show that such a SegAN framework is more effective and stable for the segmentation task, and it leads to better performance than the state-of-the-art U-net segmentation method. We tested our SegAN method using datasets from the MICCAI BRATS brain tumor segmentation challenge. Extensive experimental results demonstrate the effectiveness of the proposed SegAN with multi-scale loss: on BRATS 2013 SegAN gives performance comparable to the state-of-the-art for whole tumor and tumor core segmentation while achieves better precision and sensitivity for Gd-enhance tumor core segmentation; on BRATS 2015 SegAN achieves better performance than the state-of-the-art in both dice score and precision.&lt;/p&gt;
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