http://www.nitrc.org/forum/forum.php?forum_id=8811 <table border="0" width="100%"><tr><td align="left"/><td align="right"><a href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;cmd=Link&amp;LinkName=pubmed_pubmed&amp;from_uid=30002390">Related Articles</a></td></tr></table> <p><b>Resting-state fMRI study on drug-naive patients of essential tremor with and without head tremor.</b></p> <p>Sci Rep. 2018 Jul 12;8(1):10580</p> <p>Authors: Wang L, Lei D, Suo X, Li N, Lu Z, Li J, Peng J, Gong Q, Peng R</p> <p>Abstract<br/> This study used resting-state functional MRI (r-fMRI) to evaluate intrinsic brain activity in drug-naive patients with essential tremor (ET) with and without head tremor. We enrolled 20 patients with ET with hand and head tremor (h-ET), 27 patients with ET without head tremor (a-ET), and 27 healthy controls (HCs). All participants underwent r-fMRI scans on a 3-T MR system. The amplitude of low-frequency fluctuation (ALFF) of blood oxygen level-dependent signals was used to characterize regional cerebral function. We identified increased ALFF value in the bilateral posterior lobe of cerebellum in the h-ET patients relative to a-ET and HCs and demonstrated that h-ET is related to abnormalities in the cerebello-cortical areas, while the a-ET is related to abnormalities in the thalamo-cortical areas. In addition, we observed the ALFF abnormality in the cerebellum (left cerebellum VIII and right cerebellum VI) correlated with the tremor score in h-ET patients and abnormal ALFF in the left precentral gyrus correlated with the age at onset and disease duration in h-ET patients. These findings may be helpful for facilitating further understanding of the potential mechanisms underlying different subtypes of ET.<br/> </p><p>PMID: 30002390 [PubMed - in process]</p> en-us Copyright 2000-2026 NITRC OSI Mon, 27 Apr 2026 12:21:14 GMT http://blogs.law.harvard.edu/tech/rss NITRC RSS generator