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  <title>NITRC News Group Forum: low-dimensional-morphospace-of-topological-motifs-in-human-fmri-brain-networks.</title>
  <link>http://www.nitrc.org/forum/forum.php?forum_id=8977</link>
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	&lt;table border=&quot;0&quot; width=&quot;100%&quot;&gt;&lt;tr&gt;&lt;td align=&quot;left&quot;/&gt;&lt;td align=&quot;right&quot;&gt;&lt;a href=&quot;https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;amp;cmd=Link&amp;amp;LinkName=pubmed_pubmed&amp;amp;from_uid=30215036&quot;&gt;Related Articles&lt;/a&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;
        &lt;p&gt;&lt;b&gt;Low-dimensional morphospace of topological motifs in human fMRI brain networks.&lt;/b&gt;&lt;/p&gt;          
        &lt;p&gt;Netw Neurosci. 2018;2(2):285-302&lt;/p&gt;
        &lt;p&gt;Authors:  Morgan SE, Achard S, Termenon M, Bullmore ET, Vértes PE&lt;/p&gt;
        &lt;p&gt;Abstract&lt;br/&gt;
        We present a low-dimensional morphospace of fMRI brain networks, where axes are defined in a data-driven manner based on the network motifs. The morphospace allows us to identify the key variations in healthy fMRI networks in terms of their underlying motifs, and we observe that two principal components (PCs) can account for 97% of the motif variability. The first PC of the motif distribution is correlated with efficiency and inversely correlated with transitivity. Hence this axis approximately conforms to the well-known economical small-world trade-off between integration and segregation in brain networks. Finally, we show that the economical clustering generative model proposed by Vértes et al. (2012) can approximately reproduce the motif morphospace of the real fMRI brain networks, in contrast to other generative models. Overall, the motif morphospace provides a powerful way to visualize the relationships between network properties and to investigate generative or constraining factors in the formation of complex human brain functional networks.&lt;br/&gt;
        &lt;/p&gt;&lt;p&gt;PMID: 30215036 [PubMed]&lt;/p&gt;
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