Dear Chris,

I´ve already a related post that went unanswered, sorry if my formulation was too long, I´ll try to simplify.

My analysis is a ROI-based VLSM. Is the statistical model a linear regression with Y=percent of ROI damage for each patient and X=behavioural score?

If I correct for nuisance covariates with the Freedman-Lane Permutation -2000, is it running multiple independent regressions instead of including the nuisance variable in a single linear regression?

Thanks in advance for any help!

Best,
Noelia