sdm-help-list > Are separate independent meta-analyses multiple comparisons?Is multi-correction necessary?
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May 3, 2021  03:05 PM | shuxian yu
Are separate independent meta-analyses multiple comparisons?Is multi-correction necessary?
We performed separate meta-analyses for the different groups. We ensured that each dataset was not reused in a meta-analysis to avoid multiple comparisons.
If a literature appears in several groups, it is because several different data sets are available in that study for analysis in different groups.
In addition, we referenced several articles using similar research methods, mostly without multiple corrections, and one of them reported in the main text only those results that survived at a more conservative threshold (Z-score ≥ 5.0)(Robin Paul Wilson,2018).

I would like to know if several analyses in this case are multiple comparisons. Is it necessary to take multiple corrections (e.g. Bonferroni correction)? Thank you in advance for your answer.

P.s. SDM software (SDM, version 5.15, http://www.sdmproject.com, formerly "Signed Differential Mapping") was used for the meta-analyses.