open-discussion > Hippocampome.org updates: connectivity quantification and in vivo rhythms!
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Jun 20, 2021 03:06 PM | Giorgio Ascoli
Hippocampome.org updates: connectivity quantification and in vivo rhythms!
Dear colleagues,
The Hippocampome.org team is pleased to share the news of two substantial upgrades of this open-access knowledge base of neuron types and their properties in the rodent hippocampal formation in the last 6 months:
The release of v1.8 on 12/28/2020 included an additional 5,152 Pieces of knowledge (PoK), 6,055 Pieces of Evidence (PoE), and new browsable matrices for neurite lengths, somatic path distances, numbers of potential synapses, numbers of contacts, and connection probabilities for most of the 3120 pairs of neuron types. Reference: Tecuatl, et al. (2021) Comprehensive estimates of potential synaptic connections in local circuits of the rodent hippocampal formation by axonal-dendritic overlap. Journal of Neuroscience (8):1665-1683; doi.org/10.1523/JNEUROSCI.1193-20.2020.
The release of v1.9 on 02/27/2021 adds an additional 91 PoK, 768 PoE, and a new browsable matrix for in vivo recordings, including theta phases, sharp-wave ripple ratios, average firing rates, and more. Reference: Sanchez-Aguilera, et al. (2021) An update to Hippocampome.org by integrating single-cell phenotypes with circuit function in vivo. PLoS Biology 19(5):e3001213; doi.org/10.1371/journal.pbio.3001213.
Stay tuned for more forthcoming new data and functionality, including comprehensive Tsodyks-Markram synaptic dynamics, neuron type population counts, and annotated spiking neural network models of cognitive functions!
Best wishes for a summer filled with episodic memories and spatial navigation,
The Hippocampome.org Team
----------------
Giorgio Ascoli, PhD
University Professor
Bioengineering Department, Volgenau School of Engineering
Neuroscience Program, Krasnow Institute for Advanced Study
Director, Center for Neural Informatics, Structures, & Plasticity
MS2A1 - George Mason University, Fairfax, VA 22030-4444
Ph. +1(703)993-4383/+1(703)673-8894
Author of "Trees of the Brain, Roots of the Mind" (MIT Press, 2015)
Founding Editor-in-Chief, Neuroinformatics
The Hippocampome.org team is pleased to share the news of two substantial upgrades of this open-access knowledge base of neuron types and their properties in the rodent hippocampal formation in the last 6 months:
The release of v1.8 on 12/28/2020 included an additional 5,152 Pieces of knowledge (PoK), 6,055 Pieces of Evidence (PoE), and new browsable matrices for neurite lengths, somatic path distances, numbers of potential synapses, numbers of contacts, and connection probabilities for most of the 3120 pairs of neuron types. Reference: Tecuatl, et al. (2021) Comprehensive estimates of potential synaptic connections in local circuits of the rodent hippocampal formation by axonal-dendritic overlap. Journal of Neuroscience (8):1665-1683; doi.org/10.1523/JNEUROSCI.1193-20.2020.
The release of v1.9 on 02/27/2021 adds an additional 91 PoK, 768 PoE, and a new browsable matrix for in vivo recordings, including theta phases, sharp-wave ripple ratios, average firing rates, and more. Reference: Sanchez-Aguilera, et al. (2021) An update to Hippocampome.org by integrating single-cell phenotypes with circuit function in vivo. PLoS Biology 19(5):e3001213; doi.org/10.1371/journal.pbio.3001213.
Stay tuned for more forthcoming new data and functionality, including comprehensive Tsodyks-Markram synaptic dynamics, neuron type population counts, and annotated spiking neural network models of cognitive functions!
Best wishes for a summer filled with episodic memories and spatial navigation,
The Hippocampome.org Team
----------------
Giorgio Ascoli, PhD
University Professor
Bioengineering Department, Volgenau School of Engineering
Neuroscience Program, Krasnow Institute for Advanced Study
Director, Center for Neural Informatics, Structures, & Plasticity
MS2A1 - George Mason University, Fairfax, VA 22030-4444
Ph. +1(703)993-4383/+1(703)673-8894
Author of "Trees of the Brain, Roots of the Mind" (MIT Press, 2015)
Founding Editor-in-Chief, Neuroinformatics