Dear Andrew,
Thank you for creating this software; it has been great.
I have used NBS to identify networks that differ between three laterality groups using ANOVA. I found one significant network comprising 29 edges and 29 nodes. To understand the group differences, I then looked at the significant connections at the subject level and conducted 3 separate t-tests on the 29 significant connections using MATLAB, correcting for multiple comparisons to better understand which groups drove the differences. The results make sense, but I am wondering if this kind of post hoc analysis is appropriate for NBS, or would you suggest running 3 separate t-tests on the whole brain using NBS?
Many thanks for your help!
Ieva
Hi Leva,
your approach seems quite reasonable to me. Post-hoc t-tests will provide insight into the direction of the effects and these could be reported in your paper.
Running 3 separate t-tests using the NBS is also a possibility, but your current approach is probably the most sensible.
Andrew
Originally posted by Ieva Andrulyte:
Dear Andrew,
Thank you for creating this software; it has been great.
I have used NBS to identify networks that differ between three laterality groups using ANOVA. I found one significant network comprising 29 edges and 29 nodes. To understand the group differences, I then looked at the significant connections at the subject level and conducted 3 separate t-tests on the 29 significant connections using MATLAB, correcting for multiple comparisons to better understand which groups drove the differences. The results make sense, but I am wondering if this kind of post hoc analysis is appropriate for NBS, or would you suggest running 3 separate t-tests on the whole brain using NBS?
Many thanks for your help!
Ieva